Additional Information
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PureRegen Gel SINUS is formulated from crosslinked hyaluronic acid, purely from bacterial fermentation and contains no animal components.
The PureRegen Gel SINUS degradation profile matches the critical repair period, especially the inflammatory processes after surgery, providing an effective barrier between the mucosal surfaces to prevent adhesion. PureRegen Gel SINUS dissolves in 14 days, eliminating the need for painful packing removal and secondary damage to fresh mucous.¹ ²
Prospective, randomised, controlled multiple centre clinical studies (level 1) in China and the USA demonstrated that PureRegen Gel SINUS resulted in less adhesion, better remucosalisation, and reduced edema and crust than the control group. 3,4,5
References 1. Watelet JB, et al: Wound Healing of the Nasal and Paranasal Mucosa: A Review. American Journal of Rhinology and Allergy 16:77-84, 2002. 2. Pajic-Penavic I.: Endoscopic Monitoring of Postoperative Sinonasal Mucosa Wounds Healing. Advances in Endoscopic Surgery, Prof. Cornel Lancu (Ed.), InTech. 21:419-436, 2001. 3. Shi R., et al. The Clinical Outcomes of New Hyaluroan Nasal Dressing: A Prospective Randomised, Controlled Study. American Journal of Rhinology and Allergy 27:71-76, 2013. 4. Matheny KM, et.al. Self-crosslinked hyaluronic acid hydrogel in ethmoidectomy: A Randomised, controlled trial. American Journal of Rhinology and Allergy 28:508-513, 2014. 5. Preventing Adhesion and Keeping the ostia open after Functional Endoscopic Frontal Sinus Surgery by a Novel Crosslinked Hyaluronan Gel: Internal Data. Manuscript 2015.
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